Search results for "Standard operating procedures"

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The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance : Evidence of validity

2014

BackgroundAn international Delphi panel has defined a harmonized protocol (HarP) for the manual segmentation of the hippocampus on MR. The aim of this study is to study the concurrent validity of the HarP toward local protocols, and its major sources of variance.MethodsFourteen tracers segmented 10 Alzheimer's Disease Neuroimaging Initiative (ADNI) cases scanned at 1.5 T and 3T following local protocols, qualified for segmentation based on the HarP through a standard web-platform and resegmented following the HarP. The five most accurate tracers followed the HarP to segment 15 ADNI cases acquired at three time points on both 1.5 T and 3T.ResultsThe agreement among tracers was relatively low…

MalePathologyDiagnostic criteriaEpidemiologyImage Processinggenetics [Alzheimer Disease]HippocampusFunctional LateralityImagingpathology [Alzheimer Disease]ddc:616.89methods [Magnetic Resonance Imaging]Computer-AssistedClinical trialsddc:150methods [Image Processing Computer-Assisted]ValidationImage Processing Computer-AssistedSegmentationHARPmedicine.diagnostic_testHealth PolicyOrgan SizeAlzheimer's diseaseMiddle Agedinstrumentation [Magnetic Resonance Imaging]Manual segmentationMagnetic Resonance ImagingPsychiatry and Mental healthMagnetic resonanceBiomedical ImagingManual segmentationFemalemethods [Neuroimaging]methods [Imaging Three-Dimensional]EADC-ADNI Working Group on The Harmonized Protocol for Manual Hippocampal Volumetry and for the Alzheimer's Disease Neuroimaging Initiativemedicine.medical_specialtyHippocampal volumetry; Magnetic resonance; Alzheimer's disease; Biomarkers; Diagnostic criteria; Enrichment; Clinical trials; Validation; Harmonized protocol; Standard operating procedures; Manual segmentationConcurrent validityClinical SciencesHarmonized protocolNeuroimagingArticleHippocampal volumetryCellular and Molecular NeuroscienceImaging Three-DimensionalDevelopmental NeuroscienceNeuroimagingClinical ResearchAlzheimer DiseasemedicineHumansddc:610AgedProtocol (science)ReproducibilityInternetbusiness.industryNeurosciencesReproducibility of ResultsMagnetic resonance imagingBrain DisordersStandard operating procedurespathology [Hippocampus]EnrichmentGeriatricsThree-DimensionalNeurology (clinical)Geriatrics and GerontologyAtrophyNuclear medicinebusinessBiomarkers
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